Study Roundup

Published in November Issue             

Probability of an Obese Person Attaining Normal Body Weight: Cohort Study Using Electronic Health Records (American Journal of Public Health)

Most people with obesity are statistically unlikely to lose weight and keep it off. Researchers looked at electronic health records of a total of 278,982 people living in the U.K. over a nine-year period. The findings show those with a BMI between 30 and 35 with just one in 10 women and one in 12 men had 5% weight reduction over a year. Most people in the study were much more likely to reduce their weight by 5% in a year. Of participants termed superobese — those with BMI greater than 45 — women had a one-in-six chance, while men had a
one-in-five chance of weight reduction. Of those who lost 5% of their weight, at least half regained the weight within two years.

BMI Development and Early Adolescent Psychosocial Well-Being: UK Millennium
Cohort Study

Children who don't get enough sleep are at a higher risk of becoming overweight. New research points to early lifestyle factors such as eating breakfast and getting enough sleep early in life could predict if a child will become obese. Researchers from University College London looked at BMI in the first 10 years of a child's life, and which lifestyle factors appear to affect and predict weight gain. Children from nearly 20,000 families were studied and weight BMI was collected at ages 3, 5, 7 and 11. Children who skipped breakfast and didn’t have a regular bedtime or what was deemed enough sleep were important factors in predicting overweight or obese, as was whether the mothers smoked during pregnancy.

Childhood Bullying Victimization and Overweight in Young Adulthood: A Cohort Study (Psychosomatic Medicine)

Researchers studied over 2,000 twin children born in the UK from 1994 to 1995 and tracked them from birth until they were 18. They found that children who had been chronically bullied during elementary and middle school, were 70% more likely to be overweight at age 18 than their non-bullied counterparts. Though bullied children were more likely to come from a struggling home or have mental health issues, the connection between bullying and weight continue to exist after accounting for these and other factors. About 20% of non-bullied children became overweight by 18, compared to 29% of bullied children. The research suggests that bullying itself can directly raise the risk of becoming overweight.

Single-port Laparoscopic Sleeve Gastrectomy as a Routine Procedure in 1000

Median body mass index was 42.6 kg/m˛ (range: 33.8–84.6 kg/m˛). Median operative time was 112 minutes (range: 50–360 min) and decreased over the years. Postoperative mortality and morbidity rates were .1% and 8.1%, respectively. Relaparoscopy and/or endoscopic treatment were required to treat intra-abdominal bleeding in 24 patients (2.4%) and staple-line leakage in 28 patients (2.8%). Five hundred forty-six patients were considered for 1-year follow-up evaluation. Mean excess weight loss was 69% after 1 year and 62.2% after 2 years. Incisional hernia from the trocar site occurred in 20 (3.7%) patients. The authors concluded sleeve gastrectomy can be routinely performed using a single-incision laparoscopic technique with equivalent outcomes of surgical morbidity and weight loss compared with conventional laparoscopic surgery.

Management of Gastric Leaks after Sleeve Gastrectomy with Endoluminal Vacuum
(E-Vac) Therapy

The purpose of this study was to recognize endoluminal vacuum (E-Vac) therapy as a viable option for use in anastomotic leaks of sleeve gastrectomies. Nine patients were treated with E-Vac therapy. During treatment, an average of 10.3 procedures per patient was done to place and exchange the Endo-SPONGE. All 9 patients had resolution of leaks confirmed by upper GI series, after undergoing E-Vac therapy for an average of 50 days. The authors concluded that E-Vac therapy is a viable option for patients with staple line leak after
sleeve gastrectomy.

Screening and Brief Intervention for Obesity in Primary Care: a Parallel, Two-arm, Randomised Trial (The Lancet)

Primary care physicians in England who raised the issue obesity with their patients did not offend them and were likely to help them reach a healthy weight. Evidence suggests that physicians are concerned about offending their patients by discussing weight, but qualitative evidence from patients and this trial shows that they should be less concerned. If physicians act in accordance with guidelines, patients are likely to welcome the intervention and lose a significant amount of weight. Given that many patients consult their primary care physician at least once a year and most several times a year, this brief intervention has high reach, is practicable, and could reduce population mean weight.